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. Author manuscript; available in PMC: 2012 Dec 1.
Published in final edited form as: Expert Opin Investig Drugs. 2011 Oct 24;20(12):1717–1722. doi: 10.1517/13543784.2011.630660
Drug name Exenatide
Phase Phase II
Indication Type 2 diabetes
Route of administration Subcutaneous
Dosing 5μg twice a day for one month to improve/test tolerability and then increasing to 10 μg twice a day based on clinical response.
Chemical structure 39-amino acid peptide with a 53% homology to human GLP-1
Clinical trials Most of the clinical trials have shown a suppressive effect on appetite with a reduction of 3–6 kg of weight and improvement in metabolic and cardiovascular risk factors in non-diabetic patients.