Drug name | Exenatide |
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Phase | Phase II |
Indication | Type 2 diabetes |
Route of administration | Subcutaneous |
Dosing | 5μg twice a day for one month to improve/test tolerability and then increasing to 10 μg twice a day based on clinical response. |
Chemical structure | 39-amino acid peptide with a 53% homology to human GLP-1 |
Clinical trials | Most of the clinical trials have shown a suppressive effect on appetite with a reduction of 3–6 kg of weight and improvement in metabolic and cardiovascular risk factors in non-diabetic patients. |