Skip to main content
. Author manuscript; available in PMC: 2013 Oct 24.
Published in final edited form as: J Am Chem Soc. 2012 Oct 10;134(42):17823–17831. doi: 10.1021/ja309003x

Table 1.

Screening of Various Vinylcyclopropanes

graphic file with name nihms414185u1.jpg
entry substrate product
1 graphic file with name nihms414185t1.jpg
1 		graphic file with name nihms414185t2.jpg 5a
97%a, 1.5:1 d.r.b
39% e.e. (major)c
72% e.e. (minor)c
2 graphic file with name nihms414185t3.jpg
6 		graphic file with name nihms414185t4.jpg 5b
84%a, 2.1:1 d.r.b
29% e.e. (major)c
79% e.e. (minor)c
3 graphic file with name nihms414185t5.jpg
7 		graphic file with name nihms414185t6.jpg 5c
22%a, >20:1 d.r.b
94% e.e. (major)c
a

Isolated yield.

b

Diastereomeric ratio (d.r.) determined by 1H NMR.

c

Enantiomeric excess (e.e.) of major and minor diastereomer, respectively, determined by chiral HPLC.