Table 1.
Group of animals (n = 6-8) |
Cytokine release in BAL fluid (pg/mL) |
|||||||
---|---|---|---|---|---|---|---|---|
IL-1β | IL-6 | IL-10 | IL-12p40 | INFγ | TNFα | MCP-1 | TGFβ2 | |
PBS |
55 ± 29 |
18 ± 9 |
34 ± 12 |
458 ± 67 |
45 ± 9 |
48 ± 30 |
61 ± 37 |
84 ± 10 |
SWCNT |
8 ± 0 |
18 ± 7 |
10 ± 4 |
1173 ± 146 |
25 ± 9 |
9 ± 2 |
51 ± 22 |
165 ± 23 |
T. gondii 103 |
432 ± 227* |
408 ± 136 |
552 ± 236#* |
3468 ± 688#* |
5769 ± 1799#* |
1016 ± 466 |
2569 ± 978 |
124 ± 17 |
SWCNT/ T. gondii 103 |
165 ± 56 |
497 ± 84 |
502 ± 108 |
3752 ± 292#* |
9090 ± 1807#* |
720 ± 199 |
3558 ± 745 |
187 ± 22 |
T. gondii 104 |
229 ± 40 |
1058 ± 208#* |
612 ± 130#* |
2587 ± 409# |
8977 ± 966#* |
859 ± 246 |
8214 ± 2180#* |
286 ± 58#$ |
SWCNT/ T. gondii 104 | 288 ± 51 | 1186 ± 387#* | 798 ± 138#* | 2696 ± 565# | 7245 ± 1023#* | 1048 ± 296* | 11406 ± 2167#*$f | 358 ± 52 #*$f |
Results are presented as mean ± SEM. Statistical significance was determined with one-way ANOVA and Bonferroni’s Multiple Comparison test. # = p < 0.05 indicates significant differences from PBS, * = p < 0.05 indicates significant differences from SWCNT, $ = p < 0.05 indicates significant differences from T. gondii 103, and f = p < 0.05 indicates significant differences from SWCNT + T. gondii 103. BAL fluid samples were obtained at 7 days post-exposure.