Table 2.

Electrophysiological characteristics of LI neurons from adult mice (Ward’s)

	SF	sAHP	fAHP	ADP1	ADP2
	(N = 4)	(N = 18)	(N = 11)	(N = 29)	(N = 6)
Ri (MΩ)	1575.0 ± 103.1a	443.5 ± 37.8	421.3 ± 51.0	476.0 ± 44.5	413.3 ± 42.8
SF >> sAHP, fAHP, ADP1, ADP2
Cm (pF)	18.2 ± 4.4a	44.0 ± 3.2	44.7 ± 4.2	47.0 ± 4.2	58.2 ± 8.9
sAHP, fAHP, ADP1, ADP2 >> SF
Tau (ms)	42.0 ± 5.9	21.6 ± 1.1	18.5 ± 2.0	27.1 ± 2.1	39.3 ± 8.5
SF, ADP2 > sAHP, fAHP, ADP1
RMP (mV)	−56.2 ± 5.1	−64.8 ± 1.7	−69.6 ± 1.4	−63.1 ± 1.3	−60.7 ± 2.9
SF > fAHP
Rheobase (pA)	0	63.9 ± 10.4	71.8 ± 9.4	28.7 ± 4.1	30.8 ± 11.0
sAHP, fAHP > SF, ADP1, ADP2
Amplitude (mV)	73.1 ± 7.3	63.2 ± 3.2c	80.9 ± 4.8	95.7 ± 2.4a	60.7 ± 3.7
ADP1>> SF, sAHP, fAHP, ADP2; fAHP > sAHP, ADP2
First spike latency (ms)	192.6 ± 15.3	313.7 ± 28.7	229.0 ± 38.3	184.6 ± 15.1	240.4 ± 47.3
sAHP >> ADP1
Amplitude of early frequency adaptation (Hz)	44.9 ± 7.3	75.3 ± 5.3	66.0 ± 9.9	99.7 ± 8.3a	50.9 ± 7.5
ADP1>> SF, sAHP, fAHP, ADP2
Time constant of early adaptation (ms)	21.8 ± 4.9	25.5 ± 2.9	30.1 ± 3.7	23.5 ± 1.7	55.6 ± 11.3a
ADP2 >> ADP1, SF, sAHP, fAHP
Slope of late adaptation (Hz/s)	−12.3 ± 5.4	−23.8 ± 4.6	−33.5 ± 6.7	−38.4 ± 4.5b	−4.5 ± 10.4
ADP2 > ADP1
Maximal steady-state frequency (Hz)	41.7 ± 5.5	43.8 ± 2.4	48.9 ± 5.1	62.2 ± 4.0b	31.6 ± 3.3
ADP1 > ADP2
Duration increase	27.7 ± 8.6	25.2 ± 2.6	20.3 ± 1.3	10.2 ± 1.0a	19.9 ± 4.7
SF, sAHP, fAHP, ADP2 >> ADP1
Threshold (mV)	−52.5 ± 1.5a	−37.9 ± 1.4	−36.9 ± 1.2	−42.0 ± 0.8	−41.3 ± 1.1
sAHP, fAHP, ADP1, ADP2 >> SF; sAHP, fAHP > ADP1
Half width (ms)	1.55 ± 0.14	1.76 ± 0.07c	1.34 ± 0.07	1.08 ± 0.03a	1.65 ± 0.04
SF, sAHP, fAHP, ADP2 >> ADP1; sAHP, ADP2 > fAHP
Rise time (ms)	0.65 ± 0.03	0.69 ± 0.02	0.66 ± 0.02	0.59 ± 0.01b	0.76 ± 0.02
sAHP, fAHP, ADP2 > ADP1
Decay time (ms)	1.67 ± 0.24	1.63 ± 0.08c	1.10 ± 0.10	0.78 ± 0.03a	1.48 ± 0.08
SF, sAHP, ADP2 > fAHP >> ADP1

a, P < 0.01 compared to other groups, b, P < 0.05, compared to ADP2, c, P < 0.05 compared to fAHP.