Table 3. Comparison of biomarker levels from peripheral and coronary sinus samples in low and high BNP groups.
Peripheral Serum Samples (n = 41) | Coronary Sinus Serum Samples (n = 41) | |||||
Low BNP (n = 14)n = 14 | High BNP (n = 27)n = 27 | P | Low BNP (n = 14)n = 14 | High BNP (n = 27)n = 27 | P | |
BNP,pg/mL | 10.4 (9.4,14.1) | 58 (32,129) | <0.001 | 24 (9.8,42.3) | 115 (59,403) | <0.001 |
PICP,ng/mL | 272±43 | 267±4 | 0.74 | 331±107 | 297±10 | 0.39 |
PINP,mg/mL | 27.5±14.3 | 35.3±12.9 | 0.266 | 27.5±7.8 | 32.4±12.8 | 0.179 |
CITP,µg/L | 3.3±1.1 | 4.9±3.7 | 0.06 | 3.8±0.7 | 5.1±1.9 | 0.007 |
PIIINP,µg/mL | 2.7±1.4 | 2.2±0.8 | 0.30 | 2.4±0.5 | 2.8±1.0 | 0.11 |
TNFα,pg/mL | 4.0±2.0 | 3.7±1.1 | 0.63 | 3.2±0.5 | 3.7±1.1 | 0.03 |
IL-6,pg/mL | 1.2±1.0 | 1.9±1.6 | 0.13 | 1.9±1.3 | 3.4±2.7 | 0.02 |
IL-8, pg/mL | 6.7±2.7 | 6.5±3.2 | 0.86 | 5.7±1.7 | 6.4±3.6 | 0.46 |
hsCRP,mg/L | 1.4±1.1 | 2.7±2.7 | 0.04 | 1.2±1.1 | 2.4±1.1 | 0.04 |
Data are presented mean ± standard deviation or as median and 25th and 75th percentiles in parenthesis. BNP = B-type natriuretic peptide; IL = interleukin; hsCRP high sensitivity C-reactive protein; TNFα = tumor necrosis factor-α; PICP = carboxy-terminal; PINP = amino-terminal; CITP = carboxy-terminal telopeptide of procollagen type I; PIIINP = amino-terminal propeptide of procollagen type III.