Table 1.
Scoring results of the immunohistochemical staining in central chondrosarcoma
| Diagnosis |
pSmad1/5/8 |
pSmad2 |
Endoglin / CD105 |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Higha | % | p-valueb | Higha | % | p-valueb | Higha | % | p-valueb | |
| total |
13 / 25 |
52.0 |
|
15 / 24 |
62.5 |
|
11 / 26 |
42.3 |
|
| CCS I |
2 / 9 |
22.2 |
|
4 / 10 |
40.0 |
|
1 / 9 |
11.1 |
|
| CCS II |
7 / 10 |
70.0 |
|
6 / 8 |
75.0 |
|
7 / 10 |
70.0 |
|
| CCS III |
4 / 6 |
66.7 |
|
5 / 6 |
83.3 |
|
3 / 6 |
50.0 |
|
| high gradec | 11 / 16 | 68.8 | 0.04 | 11 / 14 | 78.6 | 0.09 | 10 / 16 | 62.5 | 0.03 |
a: number of tumor samples with high expression defined as showing a total sum score higher than 3.
b: p-value of the Fisher’s exact test for the comparison of the corresponding sample group with CCS I. Significant p-values are shown in bold.
c: high grade: grade II and grade III.