Figure 7. Three different HDAC inhibitors (trichostatin A; 5 nM), scriptaid; 500 nM) and VPA; 2 mM) have similar inhibitory effects on (A) basal and LH-induced androstenedione secretion by bovine theca cells and (B) basal and FSH-induced estrogen secretion by bovine granulosa cells.

Values are means ± SEM (n = 4 independent cultures). *p<0.05, ***p<0.001 compared to corresponding group without inhibitor.