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. 2012 Aug 21;9:76. doi: 10.1186/1743-7075-9-76

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Copyright ©2012 Olivan et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Effect of theophylline (50 mg/kg bw) on circulating TNF-α and IL-10 concentrations in rats bearing the Yoshida AH-130 ascites hepatoma. Results are mean ± SEM. The plasmatic concentrations of TNF-α and IL-10 are expressed as pg/ml of plasma. C = non-tumour-bearing rats, T = tumour-bearing rats, T + TPH = tumour-bearing rats treated with theophylline. Values that are significantly different by two-way analysis of variance (ANOVA) are indicated by: ## p < 0.01 (tumour effect); *** p < 0.001 (treatment effect).