Table 2.

Reports of brain cancer incidence in physicians, radiologists and interventionalists

STUDY, YEAR	METHODS	FINDINGS
Matanoski et al., 1975 [32]	Cohort study of mortality in 6,500 US male radiologists (years first worked 1920–1969) over a 50-year period	Excess cancer risk among radiologists compared with other physicians
Wang JX et al., 1990 [33]	Cohort study of Chinese diagnostic x-ray workers (1950 to 1985)	Trend of excess cancer risk (standardized incidence ratio 1.2 for employment duration 10–14 years; 2.3 for 15–19 years) compared to non-radiation medical workers, not available for brain cancer
Andersson M et al., 1991 [34]	Cohort study of Danish radiation therapy workers	Trend of excess cancer risk (standardized incidence ratio 1.09 with measured radiation dose < 5 mSv, and 2.23 with dose 5–50 mSv), not available for brain cancer
Carozza et al., 2000 [35]	Case–control study of occupation and glioma	Physicians at increased, albeit imprecise, risk of glioma (OR 3.5, CI 0.7- 17)
Andersen M et al., 1999 [36]	Population-based study of occupation and cancer incidence (from the 1990s to 1980s)	Brain cancer increased among physicians in general; no breakdown by specialty
Hardell et al., 2001 [37]	Case control study of 233 gliomas	Excess cancer risk of 6.0 in fluoroscopists
Blettner et al., 2007 [38]	Case control study of German patients (age 30–59 years at diagnosis) with brain cancer in 2001–2003	Occupational exposure (physicians, nurses, radiographers) with OR 2.49 (0.74–8.38) for neurinoma, OR close to 1 for glioma and meningioma
Finkelstein et al., 1998 [39]	Report of a case cluster (1990s)	Brain cancer in two interventionalists
Roguin et al., 2012 [40]	Report of a case cluster (2000s)	3 brain gliomas and 1 meningioma, left-sided, in 4 interventional cardiologists