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Outline of experimental procedures. Day 0 means that hyperglycemia was defined at 7 days after multiple low doses of STZ (MLD-STZ) treatment. SFN: Sulforaphane which was given subcutaneously at 0.5 mg/kg daily in five days of each week for 3 months. Some of these mice were sacrificed immediately at the end of the 3-month SFN treatment. The rest mice were sacrificed at 3 months after the 3-month SFN treatment. DM: diabetes.
