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. Author manuscript; available in PMC: 2013 Oct 28.
Published in final edited form as: J Control Release. 2012 Sep 6;163(2):161–169. doi: 10.1016/j.jconrel.2012.08.031

Fig. 6. Inhibition of pro-inflammatory endothelial activation by targeted MJ33 liposomes in vitro and in vivo.

Fig. 6

(a) Quantification of VCAM expression normalized to actin from cells treated +/- anti-PECAM (Ab62) ILs challenged by 10 ng/ml TNF for 4 hr. Resulting cell lysates were measured for VCAM by Western blot. Error bars represent standard deviation. **p < 0.005. (b) Quantification of VCAM expression normalized to actin in mice lung homogenates +/- anti-PECAM (Mec13) ILs challenged by intratracheally administered LPS (I mg/kg) 24 hr prior to lung harvest. Resulting lung homogenates were measured for VCAM by Western blot. Error bars represent standard deviation, n=3 for targeted and untargeted ILs. **p<0.001

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