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Advanced glycation end products and lipid peroxidation products in explanted scaffolds. (top panel) Immunohistochemical detection of carboxymethyl lysine (CML) in non-treated and PGG-treated collagen and elastin scaffolds implanted in control and diabetic rats (positive=brown). (bottom panel) Pentosidine (left) and malondialdehyde (MDA, right) content in non-treated and PGG-treated collagen and elastin scaffolds after implantation in diabetic rats. *indicates statistical significance.
