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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: J Virol Methods. 2012 Aug 4;186(1-2):126–131. doi: 10.1016/j.jviromet.2012.07.002

Fig.3.

Fig.3

Chicken IgY induced by NoV P particles blocked the binding of NoV norovirus P particles to HBGA receptors. (a) Partially purified IgY induced by NoV P particle (red line) in a wide range of dilutions can be used as a detection antibody to measure binding of NoV P particles to various saliva samples in saliva-based HBGA binding assays. The results were similar to those using guinea pig IgG induced by VLPs of strain VA387 (green line). Each data point represents an average value of six binding assays using six different type A salivas. (b) The IgY induced by NoV P particles blocked binding of norovirus VLPs to HBGA receptors (blue line). On the other hand, IgY after immunization with PBS neither reacted with P particles (blue line, a) nor showed detectable blocking (red line, b).