Table 5.
Absolute risk estimated in all samples
| Groups | Case (%) | Controls (%) | Relative risk | Absolute risk | ||
|---|---|---|---|---|---|---|
| Median (SD) | Min to Max | Median (SD) | Min to Max | |||
| Counts of risk allelesa | ||||||
| 0 to 1 | 187 (11.08) | 295 (16.70) | 0.51 (0.05) | 0.45 to 0.59 | 0.03 (0.003) | 0.03 to 0.03 |
| 2 | 327 (19.37) | 408 (23.10) | 0.65 (0.06) | 0.53 to 0.77 | 0.04 (0.003) | 0.03 to 0.04 |
| 3 | 472 (27.96) | 503 (28.48) | 0.81 (0.08) | 0.61 to 0.97 | 0.05 (0.005) | 0.04 to 0.06 |
| 4 | 404 (23.93) | 351 (19.88) | 0.96 (0.11) | 0.69 to 1.23 | 0.06 (0.006) | 0.04 to 0.07 |
| 5 | 201 (11.91) | 152 (8.61) | 1.16 (0.12) | 0.87 to 1.53 | 0.07 (0.007) | 0.05 to 0.09 |
| ≥ 6 | 97 (5.75) | 57 (3.23) | 1.45 (0.21) | 1.10 to 2.36 | 0.08 (0.012) | 0.06 to 0.14 |
| Counts of risk factorsb | ||||||
| 0 to 2 | 109 (6.61) | 277 (15.79) | 0.61 (0.20) | 0.35 to 1.14 | 0.04 (0.01) | 0.02 to 0.07 |
| 3 | 203 (12.31) | 344 (19.61) | 0.91 (0.33) | 0.47 to 2.00 | 0.05 (0.02) | 0.03 to 0.12 |
| 4 | 335 (20.32) | 386 (22.01)c | 1.22 (0.47) | 0.53 to 2.62 | 0.07 (0.03) | 0.03 to 0.15 |
| 5 | 346 (20.98) | 377 (21.49) | 1.78 (0.65) | 0.67 to 3.43 | 0.10 (0.04) | 0.04 to 0.20 |
| 6 | 338 (20.50) | 219 (12.49) | 2.44 (0.82) | 0.88 to 4.33 | 0.14 (0.05) | 0.05 to 0.25 |
| ≥ 7 | 318 (19.28) | 151 (8.61) | 3.92 (1.24) | 1.11 to 7.78 | 0.23 (0.07) | 0.06 to 0.45 |
a Based on the five SNPs; b Based on five SNPs and two risk factors; c Chose as ref. group.