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Cap-dependent metastasis-associated mRNAs
| Function | Metastasis-related gene |
|---|---|
| Cell proliferation | c-Myc |
| CDK2 | |
| Cyclin-D1 | |
| ODC | |
| Angiogenesis | VEGF |
| FGF-2 | |
| PDGF | |
| Anti-apoptotic | Mcl-1 |
| Bcl-2 | |
| Bcl-xL | |
| Survivin | |
| Invasion | MMP-9 |
| Heparanase |
CDK2, cyclin-dependent kinase 2; ODC, ornithine decarboxylase; PDGF, platelet-derived growth factor; Mcl-1, induced myeloid leukemia cell differentiation protein; Bcl-2, B-cell lymphoma 2; Bcl-xL, B-lymphoma × isoform long.
