FIGURE 7.

T2 cells loaded with exogenous gBK peptides are specifically killed by the gBK1- or gBK2-specific CTLs. gBK1- or gBK2-specific CTLs were generated in vitro and then tested against T2 cells that were separately loaded with three different exogenous peptides (1 μM) for 1 h at 37°C. The cells were washed and then labeled with [⁵¹Cr] for another hour at 37°C. The cells were then washed three times and used as target cells. (A) Data generated when gBK1-specific CTLs were used. (B) Data when gBK2-specific CTLs were tested against the various T2 cells. Representative data from three different experiments are shown. *p < 0.05 from the influenza M1 control peptide (FLU) cytotoxicity values.