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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: Autoimmunity. 2012 Jun 25;45(6):440–448. doi: 10.3109/08916934.2012.682668

Table 1.

Predictive phenotype of MRL/lpr derived mouse strains

Strain mature B cells mIgM sIgM mIgG sIgG SHM CSR
MRL/lpr (WT) yes yes yes yes yes yes
JHT.MRL/lpr no no no no no no
JHT.mIg.MRL/lpr yes Limited repertoire no no yes no
JHT.mIg.AID−/−MRL/lpr yes Limited repertoire no no no no

mIgM, membrane IgM; sIgM, secreted IgM; mIgG, membrane IgG; sIgG, secreted IgG; SHM, somatic hypermutation; CSR, class switching recombination.