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. Author manuscript; available in PMC: 2013 Sep 1.
Published in final edited form as: J Allergy Clin Immunol. 2012 Sep;130(3):572–584. doi: 10.1016/j.jaci.2012.07.025

Table 1.

Human vs. Mouse Eosinophils – Review at a Glance
  1. Eosinophilopoiesis: Hematological Origin and Development/Maturation

  2. The Defining Characteristics of Mature Eosinophils in Peripheral Circulation

    • Cell Morphology

    • Staining Properties Using Romanowsky Dye Sets

    • Electron Microscopic Morphology

    • Cell Surface Inventory

    • Evolutionary Conservation and/or Divergence of Characteristic Eosinophil-Associated Genes/Proteins

  3. Eosinophil Location and Relative Abundance at Homeostatic Baseline and Disease

  4. Eosinophil Trafficking & Recruitment

  5. Eosinophil Degranulation and Mediator Release

  6. Eosinophils as Regulators of the Immune Microenvironment

  7. The End Game: Eosinophil Turnover

  8. Conclusions/Summary