Figure 5. Effect of BQ123 and BQ788 on calcium influx in CHO cells transfected with ETA or ETB receptors.
Calcium ion mobilization was measured as described in Materials and Methods. The ET1 induced calcium influx was normalized as 100. The effect of the BQ123 or BQ788 was represented as the percent of ET-1 induced calcium influx. Three separate experiments showed similar results. * p < 0.05 compared with ET-1 stimulated calcium influx.