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. 2012 May 29;15(4):569–580. doi: 10.1007/s10456-012-9281-1

Table 1.

Biodistribution of 64Cu-cyclam-RAFT-c(-RGDfK-)4 in HuH-7 tumor-bearing mice treated with TSU-68 or vehicle after 14 days of therapy

Organ Vehicle (n = 5) TSU-68 (n = 5)
Blood 0.07 ± 0.01 0.05 ± 0.01a
Heart 0.59 ± 0.08 0.37 ± 0.06a
Lung 1.58 ± 0.24 1.08 ± 0.21a
Liver 5.37 ± 0.36 3.75 ± 0.46a
Pancreas 0.61 ± 0.13 0.55 ± 0.15
Spleen 2.86 ± 0.49 1.65 ± 0.21a
Stomach 1.94 ± 0.34 1.40 ± 0.19a
Intestine 1.58 ± 0.14 0.96 ± 0.15a
Kidney 25.4 ± 3.48 16.5 ± 3.36a
Skin 2.21 ± 0.22 1.51 ± 0.28a
Muscle 0.31 ± 0.07 0.21 ± 0.03a
Bone 0.81 ± 0.23 0.47 ± 0.06a
Tumor 2.44 ± 0.93 1.57 ± 0.53a

Tissue radioactivity was assessed 3 h after injection of 0.74 MBq of the tracer and is expressed as % ID/g (mean ± SD)

P < 0.05 versus the vehicle-treated group