Table 2.

Time taken for 10 % weight loss to occur in each experimental group

	Treatment received
Cohort	Vehicle	60 mg/kg/day sunitinib
4T1	20.25 ± 0.86 days	16.25 ± 0.66 days**
RENCA	23.25 ± 0.29 days	35.25 ± 0.60 days
Tumour free	No weight loss observed	37.00 ± 0.82 days

Mice were inoculated intravenously with 4T1-luc or RENCA-luc tumour cells, or left tumour free, and were then treated continuously with daily vehicle or daily 60 mg/kg/day sunitinib and weight loss was recorded. The time taken for 10 % weight loss to occur in each experimental group ± SEM is shown. n = 8 mice per experimental group

** P = 0.004 when compared to 4T1 tumour bearing mice treated with vehicle