Table 4.

Adjusted annual chronic obstructive pulmonary disease (COPD)–related and total health care costs^a in follow-up year

Variable	Adjusted mean COPD-related annual cost (95% CI)	Total health care cost per year (95% CI)
Patients with severe exacerbations only	$12,765 ($12,483–$13,047)	$43,042 ($42,404–$43,681)
Patients with moderate exacerbations only	$3356 ($3293–$3419)	$14,188 ($14,025–$14,351)
Patients with both severe and moderate exacerbations	$14,721 ($14,164–$15,279)	$43,385 ($42,103–$44,668)
Patients with any exacerbationsb	$7022 ($6926–$7119)	$25,894 ($25,625–$26,163)
Patients with no exacerbationsc	$1425 ($1404–$1447)	$11,747 ($11,639–$11,854)
Patients with a history of one or more exacerbationsd	$4875 ($4803–$4946)	$20,418 ($20,225–$20,611)
Patients with a history of two or more exacerbationse	$6550 ($6451–$6650)	$23,346 ($23,069–$23,622)
Patients aged 65 years or older	$4050 ($3986–$4114)	$18,038 ($17,866–$18,211)

Notes:

^aAll figures given in US dollars;

^bpatients with any exacerbations were patients with one or more severe and/or moderate exacerbations during the follow-up year;

^cpatients with no exacerbations were patients who had no severe or moderate exacerbations during the follow-up year;

^dpatients with a history of one or more exacerbations were patients who had one or more severe and/or moderate exacerbations during the baseline year – the reported mean costs shown were COPD-related annual costs during the follow-up year for this subgroup of patients;

^epatients with a history of two or more exacerbations were patients who had two or more severe and/or moderate exacerbations during the baseline year – the reported mean costs shown were COPD-related annual costs during the follow-up year for this subgroup of patients (note, this group is a subset of patients with a history of one or more exacerbations).

Abbreviation: CI, confidence interval.