Table 5.
Modela | Model i | Model ii |
---|---|---|
Random intercept for center—no explanatory variables | Random intercept for center—explanatory variables at the individual level | |
N | 799 | 799 |
Likelihood ratio | 715 | 706 |
Likelihood ratio testb | p = 0.002 | |
|
0.008 ± 0.004 (0.03) | 0.009 ± 0.005 (0.02) |
CV (%, relative to reference method) | 8.9% | 9.5% |
|
0.139 ± 0.007 (<0.001) | 0.138 ± 0.006 (<0.001) |
VPC—Variance partition coefficient | 0.05 | 0.06 |
Individual variables—effect (p values) | – | BMI −0.01 (0.002) |
Proportion of between-center variance explainedb | – | 0% |
Centers with bias deviating from the mean log-transformed ratio | Nice (FR), Heidelberg (GE), Greece (GR), Northern Italy (IT) | Nice (FR), Heidelberg (GE), Greece (GR), Northern Italy (IT) |
aFit of model iii was not significantly better than the previous one. Therefore, results are not presented
bCompared to the previous fitted model