Table 2.
Number of ovarian cancer cases with BRCA1 mutation (frequency %) | ||||
---|---|---|---|---|
Malopolska | Pomorze | |||
Unselected | Selected* | Unselected | Selected* | |
185delAG | 2/205 (0.97) | 2/162 (1.23) | 1/151 (0.66) | 0/96 |
300T>G | 11/212 (5.19) | 9/169 (5.33) | 1/151 (0.66) | 1/96 (1.04) |
3819del5 | 1/160 (0.63) | 1/117 (0.85) | 4/151 (2.65) | 2/96 (2.08) |
5382insC | 11/212 (5.19) | 3/169 (7.78) | 6/151 (3.98) | 1/96 (1.04) |
Cumulative frequency of four mutations | 1/8 (12.5) | 1/11 (9.09) | 1/13 (7.69) | 1/24 (4.17) |
* With negative family history for breast and/or ovarian cancer in I° or II° degree relatives