Table 2.

BRCA1 gene mutations in consecutive ovarian cancer cases unselected for age and family history of breast and/or ovarian cancer and with negative family history from two Polish provinces

	Number of ovarian cancer cases with BRCA1 mutation (frequency %)
	Malopolska		Pomorze
	Unselected	Selected*	Unselected	Selected*
185delAG	2/205 (0.97)	2/162 (1.23)	1/151 (0.66)	0/96
300T>G	11/212 (5.19)	9/169 (5.33)	1/151 (0.66)	1/96 (1.04)
3819del5	1/160 (0.63)	1/117 (0.85)	4/151 (2.65)	2/96 (2.08)
5382insC	11/212 (5.19)	3/169 (7.78)	6/151 (3.98)	1/96 (1.04)
Cumulative frequency of four mutations	1/8 (12.5)	1/11 (9.09)	1/13 (7.69)	1/24 (4.17)

* With negative family history for breast and/or ovarian cancer in I° or II° degree relatives