Table 2.
Carotid and common femoral arterial wall thickness, diameter, blood flow and shear rate from SCI individuals during weeks 3–6 (n = 4) and weeks 8–24 (n = 4) after a spinal cord injury
| Spinal cord injury (weeks 3–6) | Spinal cord injury (weeks 8–24) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 3 (n = 4) | 4 (n = 4) | 6 (n = 4) | P value | 8 (n = 4) | 12 (n = 4) | 16 (n = 4) | 20 (n = 3) | 24 (n = 3) | P value | |
| Carotid artery | ||||||||||
| Wall thickness (μm) | 526 ± 129 | 526 ± 122 | 525 ± 135 | 0.77 | 471 ± 32 | 494 ± 13 | 508 ± 17 | 508 ± 15 | 505 ± 13 | 0.006 |
| Diameter (mm) | 6.0 ± 0.3 | 6.1 ± 0.5 | 6.0 ± 0.4 | 0.58 | 5.6 ± 0.5 | 5.5 ± 0.4 | 5.5 ± 0.4 | 5.4 ± 0.3 | 5.8 ± 0.8 | 0.25 |
| Blood flow (ml/min) | 333 ± 102 | 326 ± 025 | 370 ± 052 | 0.26 | 282 ± 63 | 262 ± 37 | 249 ± 74 | 204 ± 65 | 264 ± 45 | 0.18 |
| Shear rate (s) | 83 ± 18 | 87 ± 15 | 102 ± 20 | 0.15 | 101 ± 12 | 106 ± 28 | 95 ± 38 | 75 ± 31 | 97 ± 28 | 0.23 |
| Common femoral artery | ||||||||||
| Wall thickness (μm) | 526 ± 169 | 532 ± 178 | 540 ± 167 | 0.10 | 479 ± 14 | 509 ± 8 | 515 ± 18 | 540 ± 25 | 557 ± 6 | <0.001 |
| Diameter (mm) | 7.2 ± 1.2 | 6.8 ± 1.3 | 7.0 ± 1.4 | 0.33 | 5.7 ± 0.6 | 6.1 ± 0.7 | 6.0 ± 0.7 | 5.8 ± 0.4 | 6.2 ± 0.1 | 0.23 |
| Blood flow (ml/min) | 249 ± 84 | 235 ± 123 | 349 ± 109 | 0.06 | 356 ± 160 | 310 ± 128 | 279 ± 81 | 229 ± 80 | 299 ± 48 | 0.92 |
| Shear rate (s) | 53 ± 13 | 48 ± 16 | 71 ± 21 | 0.023 | 91 ± 27 | 87 ± 10 | 67 ± 12 | 82 ± 12 | 56 ± 13 | 0.63 |
Data are presented as mean ± SD when three or four subjects were measured at the specific time point. P value refers to the linear mixed model (LMM) used to examine the change across time