Table 6.
AIV viral targets of differentially expressed miRNAs between lungs of infected and non-infected chicken (P < 0.05, Q < 0.05 and Ratio > 2)
| miRNA | Ratio of Infected/Non-infected (Normalized) | AIV RNA segments |
|---|---|---|
| gga-miR-153 |
Specifically expressed in infected lung |
HA, NA, PA, PB1 and PB2 |
| gga-miR-34a |
Specifically expressed in infected lung |
HA, NA, PA, PB1 and PB2 |
| gga-miR-202 |
+9.93 |
HA, M, NA, NP, NS, PA, PB1 and PB2 |
| gga-miR-32 |
+7.98 |
HA and NS |
| gga-miR-211 |
+7.45 |
HA, M, NA, NP, NS, PA, PB1 and PB2 |
| gga-miR-19b |
+6.55 |
HA, NS, PA and PB1 |
| gga-miR-18a |
+4.75 |
HA, M, NA, PB1 and PB2 |
| gga-miR-18b |
+3.62 |
HA, M, NA, PB1 and PB2 |
| gga-miR-155 |
+3.55 |
HA, NA, NP, NS and PB1 |
| gga-miR-15a |
+3.48 |
HA, M NP, NS and PB2 |
| gga-miR-223 |
+3.19 |
HA, NA, PB1 and PB2 |
| gga-miR-30b |
+3.06 |
M and NA |
| gga-miR-142-3p |
+2.84 |
HA, NA, PA, PB1 and PB2 |
| gga-miR-106 |
+2.83 |
HA, NA, PA, PB1 and PB2 |
| gga-miR-20a |
+2.78 |
HA, NA, NP, PB1 and PB2 |
| gga-miR-146a |
+2.59 |
HA, M, NA, NP, NS, PA, PB1 and PB2 |
| gga-miR-20b |
+2.41 |
HA, M, NA, NP, NS, PB1 and PB2 |
| gga-miR-29a |
+2.36 |
HA, M, NA, NP, PA, PB1 and PB2 |
| gga-miR-29c |
+2.36 |
HA, M, NA, NP, PA and PB1 |
| gga-miR-24 |
+2.34 |
HA, M, NA, NP, NS, PA, PB1 and PB2 |
| gga-miR-7b |
+2.33 |
HA, M, NA, PA, PB1 |
| gga-miR-17-5p |
+2.32 |
HA, M, NA, NP, PA, PB1 and PB2 |
| gga-miR-23b |
+2.25 |
HA, M, PA and PB1 |
| gga-miR-17-3p |
+2.15 |
HA, M, NA, NP, PA and PB2 |
| gga-miR-92 |
+2.07 |
HA, M, NP, NS, PB2 |
| gga-miR-206 |
−2.86 |
HA, NA, NP, PB1 and PB2 |
| gga-miR-301 |
−3.03 |
HA, NA, PB1 and PB2 |
| gga-miR-187 | −4.35 | NA, NP, PB1 and PB2 |
Note: + Up-regulated with AIV infection; - Down-regulated with AIV infection.