Table 4. Association of CR1 polymorphisms, ABO blood group in treatment outcome patients with severe malaria.
| Markers | Dead | Survivors | P value, OR (95%CI) |
| CR1 exon 22 | (n = 44) | (n = 450) | |
| AA | 20 (46) | 91 (20) | Ref, 1 |
| AG | 16 (36) | 192 (43) | 0.008, 2.63 (1.30 to 5.32) |
| GG | 8 (18) | 167 (37) | 0.0003, 4.58 (1.94 to 10.83) |
| A | 56 (64) | 374 (42) | Ref, 1 |
| G | 32 (36) | 526 (58) | 0.0001, 2.46 (1.56 to 3.87) |
| CR1 intron 27 | (n = 44) | (n = 450) | |
| AA | 27 (61) | 140 (31) | Ref, 1 |
| AT | 13 (30) | 197 (44) | 0.002, 2.92 (1.45 to 5.86) |
| TT | 4 (9) | 113 (25) | 0.0005, 5.44 (1.85 to 16.03) |
| A | 67 (76) | 477 (53) | Ref, 1 |
| T | 21 (24) | 423 (47) | <0.0001, 2.82 (1.70 to 4.70) |
| Blood groups | (n = 30) | (n = 358) | |
| O+ | 6 (20) | 119 (33) | Ref, 1 |
| A+ | 6 (20) | 65 (18) | 0.35, 0.54 (0.16 to 1.76) |
| B+ | 17 (57) | 137 (39) | 0.07, 0.40 (0.15 to 1.06) |
| AB+ | 1 (3) | 37 (10) | 1.00, 1.86 (0.21 to 16.01) |
| Non O (A++ B+ + AB+) | 24 (80) | 239 (67) | 0.15, 0.50 (0.19 to 1.26) |
NOTE: Data are no. (%) of participants unless otherwise specified. CM: cerebral malaria; MOD: multi-organ dysfunction; NCSM: non-cerebral severe malaria; UM: uncomplicated malaria; OR: odds ratio; CI: confidence interval.