Figure 3. GRA induces CD19⁺ cell accumulation in the lamina propria in uninfected and rotavirus infected mice.

Mice (n = 5 mice per group) were administered GRA or vehicle by oral gavage, and then mock-infected or infected with EW. Two dosing schedules were used: 1) GRA or vehicle alone was administered one day pre-infection and then one post-infection (pre/post), or 2) every two days through the course of infection. Nine days post-infection, cell populations isolated from the MLNs, PPs and LP were analyzed by flow cytometry for changes in B (CD19⁺) and T (CD4⁺ and CD8⁺) cells. *p<0.05, **p<0.01. Error bars are SEM.