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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: Am J Cardiol. 2012 Aug 21;110(11):1679–1686. doi: 10.1016/j.amjcard.2012.07.040

Table 4. Characteristics by Cardiac Magnetic Resonance (CMR)-derived Median Left Ventricular Mass Index (LVMi).

Variable CMR-LVMi
(<55 mg/m2)
(n=45)
CMR-LVMi
(>55 mg/m2)
(n=46)
p Value
Age of chemotherapy (yrs) 42 (18) 43 (17) 0.69
Male 24 (45%) 29 (55%) 0.39
Chest radiation 19 (63%) 11 (37%) 0.07
Anthracycline dose (mg/m ) 317 (76) 235 (63) <0.0001
Major adverse cardiac events 40 (77%) 12 (23%) <0.0001
Chemo to heart failure (months, mean, mths) 91 (81) 105 (90) 0.43
Heart failure stage C 39 (52%) 35 (48%) 0.28
Diabetes Mellitus 6 (55%) 5 (45%) 0.75
Hypertension 18 (51%) 17 (49%) 0.83
Atrial fibrillation 10 (50%) 10 (50%) 1.00
Systolic blood Pressure (mmHg) 116 (15) 115 (17) 0.51
Diastolic blood Pressure (mmHg) 73 (13) 70 (11) 0.21
Heart rate (beats/min) 71 (13) 74 (13) 0.37
Medication
ACE/ARB 38 (51%) 37 (49%) 0.78
Beta-blocker 38 (51%) 37 (49%) 0.76
Spironolactone 13 (62%) 8 (38%) 0.12
QRS duration (ms) 96 (14) 96 (18) 0.99
Glomerular filtration rate (ml/min/1.73m ) 72 (23) 84 (23) 0.02
Echocardiography:
Estimated pulmonary artery systolic pressure (mmHg) 33 (10) 33 (10) 0.95
Left ventricular mass index by echo (gm/m2) 80 (19) 76 (16) 0.33
Cardiac Magnetic Resonance
Indexed left ventricular end diastolic volume (ml/m2) 97 (21) 88 (21) 0.05
Indexed left ventricular end systolic volume (ml/m ) 63 (18) 55 (14) 0.04
Left ventricular ejection fraction (%) 36 (8) 36 (7) 0.62
Indexed right ventricular end diastolic volume (ml/m2) 80 (20) 77 16) 0.38
Indexed right ventricular end systolic volume (ml/m ) 44 (15) 42 (15) 0.56
Right ventricular ejection fraction (%) 45 (9) 46 (10) 0.68
Relative T2 signal intensity 1.4 (0.2) 1.5 (0.2) 0.36
Late gadolinium enhancement 3 (7%) 2 (4%) 0.56
Late gadolinium enhancement volume 8.9 (4.6) 4.4 (1.1) 0.22

All data are mean (SD) unless otherwise indicated