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. 2012 Nov 14;18(42):6036–6059. doi: 10.3748/wjg.v18.i42.6036

Table 6.

Operating characteristics of serological markers to detect the celiac disease in adults[178] (adapted)

Serological tests Sensitivity Specificity Predictive value Likelihood ratio
95% CI (%) 95% CI (%) Positive Negative Positive Negative
IgG AGA 57-78 71-87 0.2-0.9 0.4-0.9 1.96-6 0.25-0.61
IgA AGA 55-100 71-100 0.3-1.0 0.7-1.0 1.89-∞ 0-0.63
IgA EMA 86-100 98-100 0.98-1.0 0.8-0.95 43-∞ 0-0.14
IgA TGA 77-100 91-100  > 0.9  > 0.95 8.55-∞ 0-0.25
IgA TGA and EMA 98-100 98-100  > 0.9  > 0.95 49-∞ 0-0.02

IgG: Immunoglobulin G; IgA: Immunoglobulin A; AGA: Anti-gliadin antibodies; EMA: Endomysial; TGA: Transglutaminase.