Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Fitness costs of Myx-resistant mutants after 0, 1, and 2 serial passages
| RNAP subunit and mutationa | No. of serial passages | Fitness cost (% per generation [± SEM]) |
|---|---|---|
| β 1080 (1275) Val → Ile | 0 | 8 (±2) |
| 1 | 9 (±1) | |
| 2 | 9 (±1) | |
| β¢ 334 (345) Lys → Asn | 0 | 6 (±2) |
| 1 | 6 (±1) | |
| 2 | 8 (±1) |
Residues are numbered as in S. aureus RNAP and, in parentheses, as in E. coli RNAP.
