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. 2012 Dec;56(12):6389–6392. doi: 10.1128/AAC.00747-12

Fig 1.

Fig 1

The VanN-type resistance operon structure and the predicted ORFs found around the resistance region of E. faecium GU121-1. The upper panel shows the operon structure located on the conjugative plasmid found in the first reported VanN-type vancomycin-resistant E. faecium UCN71 clinical isolate in France (GenBank accession number: JF802084). The lower panel shows the operon structure and the predicted ORFs located on the chromosomal DNA of E. faecium GU121-1 (AB701345). The horizontal open arrows indicate ORFs and their direction of transcription. The gray-colored ORFs show the VanN-type resistance gene clusters. The thick horizontal lines behind the ORFs show the DNA sequence regions determined. The thick black lines indicate regions corresponding to the published DNA sequence data of UCN71 (6,750 bp). The thick gray lines indicate the plasmid DNA sequence regions determined in this study (12,344 bp). The promoter regions (−35 and −10 sequences) for vanN genes are shown in detail.