Table 1.
Susceptibility to quinolones of mutants obtained at different concentrations of ofloxacin
| Strain | Concn (μg/ml) of ofloxacin for selection (no. of mutants tested) | Highest MIC (MIC range) (μg/ml)a |
|||
|---|---|---|---|---|---|
| Norfloxacin | Ofloxacin | Nalidixic | Ciprofloxacin | ||
| GGL199 | 2 (12) | 128 (64–128) | 16 (8–16) | >128 (128–>128) | 16 (4–16) |
| 4 (12) | 128 (64–128) | 16 (4–16) | >128 (128–>128) | 16 (4–16) | |
| 8 (9) | 128 (A) | 16 (A) | >128 (A) | 16 (A) | |
| D457 | 2 (10) | 64 (16–64) | 16 (2–16) | 64 (16–64) | 16 (2–16) |
| 4 (12) | 64 (16–64) | 16 (4–16) | 128 (16–128) | 16 (4–16) | |
| 8 (16) | 64 (A) | 16 (8–16) | >128 (64–>128) | 16 (A) | |
a
Among the several tested mutants in each situation, the table shows the MIC of the mutant presenting the highest MIC and the range of MICs for all of them. A, all the tested mutants presented the same MIC.