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MIC data determined for fluconazole and voriconazole (with or without 10 μM FK506) and amphotericin Ba
| Isolateb | MIC (μg ml−1) |
||||
|---|---|---|---|---|---|
| CG44 | CG388 | CG1012 | CG852 | CG872 | |
| FLC | 64 | 64 | 64 | 128 | 64 |
| FLC + FK506 | 32 | 32 | 32 | 8 | 4 |
| VRC | 2 | 2 | 2 | 2 | 1 |
| VRC + FK506 | 0.5 | 0.5 | 0.5 | 0.125 | 0.0625 |
| AMB | 2 | 2 | 2 | 8 | 8 |
FK506 is a putative multidrug efflux inhibitor.
Additional isolates (CG25, CG26, CG27, CG29, and CG30) selected for ERG2 sequencing exhibited the same azole and polyene sensitivity as CG44, CG388, and CG1012.
