Fig 5.

The bacteriophage cocktail has a limited impact on 55989Str bacteria in the colon and feces of colonized mice. Three groups of mice colonized with E. coli 55989Str on day 0 received, on day 3, bacteriophage-free drinking water (white circles) or drinking water containing a cocktail of bacteriophages at 3 × 10⁸ PFU/ml (gray circles) or 3 × 10¹⁰ PFU/ml (black circles) for 24 h only. The concentrations of bacteria (A) and bacteriophages (B) were determined on days 4 and 7. The experiments were performed in duplicate or triplicate (n = 10 to 15 per condition). Two asterisks indicate P values of <0.01, and three asterisks indicate P values of <0.001.