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. 2012 Oct 8;13(10):12857–12879. doi: 10.3390/ijms131012857

Figure 2.

Figure 2

Crystal structures of fragment complexes with BACE-1. The chemical structures of the protonated forms of the compounds are shown, and, where determined, IC50 values are shown. (a) 1-aminoisoquinoline; (b) 2-aminoquinoline; (c) 2-amino-3- (benzylamino)pyridine; (d) 4-(4-fluorobenzyl)piperidine.