Table 1.
Methylation/deletion frequencies for 35 genes with the highest percent of changes in ovarian cancer.
| No. | NotI-site | Gene | Locus | Event frequency, (%) | |
|---|---|---|---|---|---|
|
| |||||
| Met/Del | Met/Del without no info | ||||
| 1 | NR1-XM13C | IQSEC1 | 3p25.2 | 33 (6/18) | 38 (6/16) |
| 2 | NL1-CJ4R (C) | NKIRAS1/RPL15 | 3p24.2 | 33 (6/18) | 35 (6/17) |
| 3 | NL4-BB6R (C) | THRB | 3p24.2 | 33 (6/18) | 38 (6/16) |
| 4 | NL3-CA11RS | LRRC3B | 3p24 | 33 (6/18) | 35 (6/17) |
| 5 | NLJ-003RD | RBSP3(CTDSPL) | 3p21.3 | 33 (6/18) | 33 (6/18) |
| 6 | NR1-KA8R (C) | THRB | 3p24.2 | 28 (5/18) | 56 (5/9) |
| 7 | NL1A401R (D) | ITGA9 | 3p21.3 | 28 (5/18) | 29 (5/17) |
| 8 | NL3A006R (D) | NBEAL2 | 3p21.31 | 28 (5/18) | 33 (5/15) |
| 9 | NL3A001R (D) | GNAI2 | 3p21.31 | 28 (5/18) | 28 (5/18) |
| 10 | NL1-DE18R | GATA2 | 3q21.3 | 28 (5/18) | 28 (5/18) |
| 11 | NL4-BH3R (C) | GATA2 | 3q21.3 | 28 (5/18) | 28 (5/18) |
| 12 | NR1-PD1R | ZIC4 | 3q24 | 28 (5/18) | 31 (5/16) |
| 13 | NL3003R (U) | GORASP1/TTC21A | 3p22–p21.33 | 22 (4/18) | 24 (4/17) |
| 14 | NR1-AN24RS | ABHD5/C3orf77 | 3p21 | 22 (4/18) | 22 (4/18) |
| 15 | NR1-WE11RS | CGGBP1 | 3p12–p11.1 | 22 (4/18) | 24 (4/17) |
| 16 | NL3-CI2R (C) | LOC285205 | 3p13.12 | 22 (4/18) | 27 (4/15) |
| 17 | NR1-WD21R (C) | NEK11/NUDT16 | 3q22.1 | 22 (4/18) | 44 (4/9) |
| 18 | NR5-IO11R (C) | PAQR9 | 3q23 | 22 (4/18) | 25 (4/16) |
| 19 | NR1-AK24R | BCL6 | 3q27 | 22 (4/18) | 24 (4/17) |
| 20 | NL6-FJ5R (C) | LRRN1 | 3p26.2 | 17 (3/18) | 17 (3/18) |
| 21 | NR1-KJ5R (C) | FBLN2 | 3p25.1 | 17 (3/18) | 19 (3/16) |
| 22 | NR1-PL22R (C) | LOC285375 | 3p25.1 | 17 (3/18) | 18 (3/17) |
| 23 | NL4-BK12R (C) | WNT7A | 3p25 | 17 (3/18) | 18 (3/17) |
| 24 | NL1308R (D) | MOBP | 3p22.1 | 17 (3/18) | 19 (3/16) |
| 25 | NR1-NC7RS | PPM1M | 3p21.2 | 17 (3/18) | 19 (3/16) |
| 26 | NR1-NJ9R (C) | PRICKLE2 | 3p14.1 | 17 (3/18) | 18 (3/17) |
| 27 | NL1-BA6R | FOXP1 | 3p14.1 | 17 (3/18) | 17 (3/18) |
| 28 | NL6-F020R (C) | DCBLD2 | 3q12.1 | 17 (3/18) | 19 (3/16) |
| 29 | NL1-GK21R (C) | ROPN1/KALRN | 3q13.3 | 17 (3/18) | 21 (3/14) |
| 30 | NL1290R (D) | CHST13 | 3q21.3 | 17 (3/18) | 17 (3/18) |
| 31 | NL2A230R | ABTB1/PODXL2 | 3q21 | 17 (3/18) | 17 (3/18) |
| 32 | NL4-DJ11RS | TRH | 3q13.3–q21 | 17 (3/18) | 18 (3/17) |
| 33 | NL1A079R (D) | EPHB1 | 3q21–q23 | 17 (3/18) | 19 (3/16) |
| 34 | NL1-FK10R (C) | PPP2R3A | 3q22.1 | 17 (3/18) | 21 (3/14) |
| 35 | NR1-NH1R (C) | FGF12 | 3q28 | 17 (3/18) | 18 (3/17) |