Table 3.

Early detection and discrimination of ovarian cancer groups with different histological characteristics using the set of 10 selected markers.

Use	Sets of markers
Early detection	NKIRAS1/RPL15, THRB, RBPS3 (CTDSPL), IQSEC1, NBEAL2, ZIC4, LOC285205, FOXP1 Sp = (94 ± 5)% Sn = (72 ± 11)% p < 0.01
Discrimination of BOA and EOC	NKIRAS1/RPL15, THRB, RBPS3 (CTDSPL), IQSEC1, NBEAL2, ZIC4, LOC285205, FOXP1 Sp = (71 ± 17)% Sn = (72 ± 11)% p = 0.04
Discrimination of Stages I + II and Stages III + IV	LOC285205, CGGBP1, EPHB1, NKIRAS1/RPL15 Sp = (88 ± 12)% Sn = (80 ± 13)% p < 0.01

Note: Sp, specificity; Sn, sensitivity of the set. p-Parameter shows significance of compared groups distinction, calculated using Fisher exact test and χ² criteria.