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Whole-lung cytokine expression pattern following C. neoformans infection. Whole-lung protein was collected at day 14 after intratracheal infection with 104 CFU of C. neoformans ATCC 24067. An individual sandwich ELISA was performed on the supernatant to determine the level of Th1 (CXCL10 and IFN-γ), Th17 (IL-17), and Th2 (IL-5, IL-13) cytokines (n = 3 to 5 mice for each strain; **, P < 0.01; ***, P < 0.001).
