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Immune response elicited in the cecum of streptomycin-pretreated C57BL/6 and TLR2-deficient (TLR2-/-) mice after infection with wild-type S. Typhimurium and a csgBA mutant (curli deficient). Transcript levels of Il17a (A), Il22 (B), and Ifng (C) were measured by quantitative real-time PCR at 48 h after infection. Bars represent changes in mRNA levels compared to a group of mock-infected mice from the same time point (geometric means and standard errors). ns, not significant.
