Fig 7.
IL-6 intestinal tissue expression during C. difficile infection in mice. (A1) IL-6 immunohistochemistry (IHC) in uninfected, infected, and ATL801-treated infected C57BL/6 mice. (A2) Mean IHC scores were from combined enterocyte, lamina propria, and submucosa scores from 3 representative mice per group (P < 0.0007 by ANOVA with Bonferroni's multiple comparison test). (B1) IL-6 IHC in infected wild-type (WT; n = 7) littermate and infected A2BAR knockout (KO; n = 5) littermate. (B2) Enterocyte IHC scores (unpaired two-tailed t test). (B3) Submucosa IHC scores (unpaired two-tailed t test).