Fig 1.

UPEC YbcL suppresses transepithelial PMN migration in vitro. 5637 bladder epithelial cell monolayers grown on Transwell inserts were infected at their apical surfaces with the indicated strains of E. coli or mock infected, and freshly isolated human PMN were added at the basolateral surface. The number of PMN recruited to the apical surface was enumerated at 1 h p.i. and is shown normalized to input PMN. Infection with MG1655 or UTI89 ΔybcL elicited significantly more PMN than that with wild-type UTI89 (*, P < 0.0001).