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C. jejuni outer membrane vesicles (OMVs) induce IL-8 from T84 intestinal epithelial cells via a CDT-independent mechanism. T84 IEC responses to 24 h of coincubation with C. jejuni wild-type strain 11168H or 11168H cdtA mutant (each at a MOI of 100:1) or with 11168H OMVs or 11168H cdtA mutant OMVs (each at 100 μg and 10 μg) were assessed. Levels of IL-8 secreted were quantified using a human IL-8 ELISA. ns, no significant difference.
