Figure 4. Influence of blood O₂ on leg perfusion and sympathetic nerve activity.

Relationship between leg blood flow or total muscle sympathetic nerve activity versus arterial oxyhaemoglobin and in healthy humans exposed to normoxia, hypoxia, carbon monoxide inhalation in normoxia, and carbon monoxide inhalation in hyperoxia_. Modified from González-Alonso et al. (2001) and Hanada et al. (2003). Note that the integrated MSNA vs. arterial graph also depicts data from a published study during hyperoxia (Seals et al. 1991).