hGfap-Cre-mediated recombination in glial cells. (A) Recombination in oligodendrocyte precursor cells indicated by colabeling with NG2 and Cre activity-dependent reporter GFP. CC, corpus callosum; Stm, striatum; Ctx, cortex. (B) Cre-mediated recombination in Olig2+ oligodendrocytes and GFAP+ astrocytes, indicated by arrows and asterisks, respectively. (C) Lack of recombination in IBA1+ microglia. Scale bar, 20 μm.