Fig 5.

Pseudotyped viral entry of the wild type, neutralization-resistant VC10042.y22.05 clone and of two reversion mutants, R373M and N386D, measured in U87.CD4.CCR5 (A) and TZM-bl (B) cell lines. Viral entry in RLU at 10 ng p24/well is reported, with statistically significant differences in entry denoted by an asterisk. Entry among the isolates were compared using a two-tailed unpaired t test, with a significance cutoff of P = 0.05. Where appropriate, significant P values are listed. NS, P values are nonsignificant.