Fig 1.

AP33 Fab in complex with its E2 epitope. (A) Overview of peptide 8741 bound in the AP33 Fab combining site. The Fab heavy and light chains are colored dark blue and cyan, respectively. The positions of the CDR loops are labeled. The peptide is colored magenta. (B) Stereoview of the Fo-Fc electron density map (green), contoured at 3σ, superimposed on the peptide. Peptide residues are numbered according to the corresponding residues in the E2 glycoprotein. (C) Stereoview of the surface of AP33 Fab (colored by electrostatic surface potential) with the peptide displayed as sticks with yellow carbon atoms. The figures were produced using the software program PyMOL (www.pymol.org).