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HSV-1 replication in human primary macrophages. (A) Herpesvirus proteins identified and quantified in the HSV-1-infected macrophage secretomes after 18 hpi. (B) HSV-1 replication kinetics in human primary macrophages measured by HSV-1 gD Western blotting from total cell lysates at different time points: 6 and 18 h for control (CTR) and IFN-β-primed macrophages and 3, 6, 9, 14, and 18 hpi for IFN-β-primed and HSV-1-infected macrophages.
