Table 2. Measurements of obesity parameters, serum lipids and glucose in female offspring.

Pregnant mice were dosed by gavage with vehicle (olive oil) or MEHP (0.5, 0.25 or 0.05 mg/kg of b.w.) from day 12 of gestation until day 7 of lactation (PND 7 of offspring). The b.w., liver weight, fat pads weight, the percentage of adipose tissue weight to b.w., and serum lipids and glucose levels were measured in 8-week-old female offspring. Values are means±S.E.M. (n=16 vehicle-treated female pups from five litters; n=10 MEHP-treated (0.5 mg/kg of b.w.) female pups from three litters; n=12 MEHP-treated (0.25 mg/kg of b.w.) female pups from three litters; n=10 MEHP-treated (0.05 mg/kg of b.w.) female pups from three litters). *P<0.05.

		MEHP dose (mg/kg of b.w.)
Parameter	Vehicle	0.5	0.25	0.05
b.w. (g)	15.86±0.16	15.48±0.24	15.51±0.13	16.05±0.84
Liver weight (g)	0.82±0.03	0.77±0.02	0.77±0.01	0.84±0.02
Parametrial fat pad weight (g)	0.15±0.01	0.15±0.01	0.14±0.01	0.15±0.01
Perirenal fat pad weight (g)	0.05±0.01	0.06±0.00	0.06±0.01	0.08±0.02
Adipose tissue weight/b.w. (%)	1.37±0.09	1.36±0.10	1.31±0.11	1.38±0.12
Cholesterol (mmol/l)	2.23±0.06	2.36±0.09	2.18±0.06	2.10±0.13
TAG (mmol/l)	0.87±0.05	0.87±0.06	0.93±0.04	0.77±0.05
Glucose (mmol/l)	3.35±0.08	3.61±0.16	4.01±0.21*	3.84±0.22