Skip to main content
. 2012 Oct 15;109(44):18084–18089. doi: 10.1073/pnas.1206411109

Fig. 1.

Fig. 1.

FTN_0818 is required for rapid phagosomal escape. (A and B) Macrophages were infected with the indicated strains, and colony-forming units were quantified at 30 min pi (A) or qRT-PCR was used to measure the expression of iglA and normalized to the expression of uvrD at 30 min and 4 h pi (B). (C and D) Transmission electron microscopy of infected macrophages at 3 h pi (arrows, intact FCP). (E) Phagosomal escape of WT (black) and ΔFTN_0818 (gray) was quantified 30 min to 6 h pi. One hundred bacteria per condition were viewed and the percentage of phagosomal escape was determined for three independent experiments. *P < 0.05; **P < 0.001; ***P < 0.0001.